ANNX Bull Call Spread Strategy

ANNX (Annexon, Inc.), in the Healthcare sector, (Biotechnology industry), listed on NASDAQ.

Annexon, Inc. is a biopharmaceutical company currently engaged in clinical trials, dedicated to the discovery and advancement of therapies for a variety of autoimmune, neurodegenerative, and ophthalmic conditions. Central to its approach is the C1q molecule, which initiates the classical complement pathway. The company targets this pathway to address specific disease mechanisms, such as those seen in antibody-mediated autoimmune disorders and complement-driven neurodegeneration. The company's developmental pipeline features several promising candidates. ANX005, a monoclonal antibody, is in advanced clinical testing, undergoing Phase II/III trials for Guillain-Barré syndrome, as well as Phase II trials for warm autoimmune hemolytic anemia, Huntington's disease, and amyotrophic lateral sclerosis. Another candidate, ANX009, is currently in Phase Ib studies for lupus nephritis.

ANNX (Annexon, Inc.) trades in the Healthcare sector, specifically Biotechnology, with a market capitalization of approximately $873.3M, a beta of 1.22 versus the broader market, a 52-week range of 2.03-7.18, average daily share volume of 3.2M, a public-listing history dating back to 2020, approximately 93 full-time employees. These structural characteristics shape how ANNX stock options price implied volatility around earnings windows, capital events, and macro-driven sector rotations.

A beta of 1.22 places ANNX roughly in line with broader market moves, so the strategy payoff and realized volatility track the index-equivalent baseline.

What is a bull call spread on ANNX?

A bull call spread buys an at-the-money call and sells an out-of-the-money call at a higher strike for defined risk and defined reward bounded by the strike width.

ANNX snapshot

As of August 14, 2026, spot at $5.24, ATM IV 246.10%, IV rank 46.94%, expected move 70.55%. The bull call spread on ANNX below is built from the end-of-day chain, with strikes snapped to listed contracts and premiums pulled from the bid/ask midpoint at a 35-day expiry.

Why this bull call spread structure on ANNX specifically: ANNX IV at 246.10% is mid-range versus its 1-year history, so strategy selection should anchor more to the directional thesis than to the IV regime, with a market-implied 1-standard-deviation move of approximately 70.55% (roughly $3.70 on the underlying). The 35-day window matched to the front-month expiry keeps theta exposure bounded while still capturing the post-snapshot move; longer-dated ANNX expiries trade a higher absolute premium for lower per-day decay. Position sizing on ANNX should anchor to the underlying notional of $5.24 per share and to the trader's directional view on ANNX stock.

ANNX bull call spread setup

The ANNX bull call spread below is built from the end-of-day chain, with each option leg priced at the bid/ask midpoint of its listed strike. With ANNX at $5.24 on that close, the first option leg uses a $5.24 strike; additional legs (when the strategy has them) anchor to spot-relative offsets. Premiums come from the bid/ask midpoint on the listed ANNX chain at a 35-day expiry; the cross-strike IV skew is reflected directly in the per-leg values rather than approximated. Quantity sizing assumes one contract per option leg (or 100 ANNX shares for the stock leg in covered calls and collars).

ActionTypeStrike / BasisPremium (est)
Buy 1Call$5.24N/A
Sell 1Call$5.50N/A

ANNX bull call spread risk and reward

Net Premium / Debit
N/A
Max Profit (per contract)
Unbounded
Max Loss (per contract)
Unbounded
Breakeven(s)
None on modeled curve
Risk / Reward Ratio
N/A

Max profit equals strike width minus net debit times 100; max loss equals net debit times 100. Breakeven is long-call strike plus net debit.

ANNX bull call spread payoff curve

Modeled P&L at expiration across a range of underlying prices for the bull call spread on ANNX. Each row is one sampled price point from the computed payoff curve; the full curve uses 200 price points internally before being summarized into 10 rows here.

When traders use bull call spread on ANNX

Bull call spreads on ANNX reduce the cost of a bullish ANNX stock position by selling a higher-strike call; suited to moderate-move theses where price reaches but does not vastly exceed the short strike.

ANNX thesis for this bull call spread

The market-implied 1-standard-deviation range for ANNX extends from approximately $1.54 on the downside to $8.94 on the upside. A ANNX bull call spread caps both the risk and the reward of a bullish position; relative to an outright long call on ANNX, the spread reduces the cost basis but limits the maximum profit to the strike width minus net debit. Current ANNX IV rank near 46.94% is mid-range against its 1-year distribution, so the IV signal is neutral; the bull call spread thesis on ANNX should anchor more to the directional view and the expected-move geometry. As a Healthcare name, ANNX options can move on sector-level news flow (peer earnings, regulatory updates, industry-specific macro data) in addition to ANNX-specific events.

ANNX bull call spread positions are structurally moderately bullish; the modeled P&L assumes European-style exercise at expiration and ignores early assignment, transaction costs, dividends paid before expiry on the stock leg (when present), and the bid-ask spread on the listed chain. ANNX positions also carry Healthcare sector concentration risk; news flow inside the sector (peer earnings, regulatory shifts, supply-chain headlines) can move ANNX alongside the broader basket even when ANNX-specific fundamentals are unchanged. Long-premium structures like a bull call spread on ANNX are particularly exposed to IV-crush risk through scheduled events (earnings, FDA decisions, central-bank meetings) where IV typically contracts post-event regardless of the directional outcome. Always rebuild the position from current ANNX chain quotes before placing a trade.

Frequently asked questions

What is a bull call spread on ANNX?
A bull call spread on ANNX is the bull call spread strategy applied to ANNX (stock). The strategy is structurally moderately bullish: A bull call spread buys an at-the-money call and sells an out-of-the-money call at a higher strike for defined risk and defined reward bounded by the strike width. With ANNX stock at $5.24 on the most recent close, the strikes shown on this page are snapped to the nearest listed ANNX chain strike and the premiums come straight from that session's bid/ask midpoint.
How are ANNX bull call spread max profit and max loss calculated?
Max profit equals strike width minus net debit times 100; max loss equals net debit times 100. Breakeven is long-call strike plus net debit. For the ANNX bull call spread priced from the end-of-day chain at a 30-day expiry (ATM IV 246.10%), the computed maximum profit is unbounded per contract and the computed maximum loss is unbounded per contract. Live intraday quotes will differ as the chain moves through the trading session.
What is the breakeven for a ANNX bull call spread?
The breakeven for the ANNX bull call spread priced on this page is no defined breakeven on the modeled curve at expiration, derived from the end-of-day chain's premiums. Breakeven is the underlying price at which the strategy's P&L crosses zero ignoring transaction costs and assignment risk. The ANNX market-implied 1-standard-deviation expected move in the same options snapshot is approximately 70.55%; if the move sits well outside the breakeven distance, the structure's risk-reward becomes correspondingly tighter.
When should you consider a bull call spread on ANNX?
Bull call spreads on ANNX reduce the cost of a bullish ANNX stock position by selling a higher-strike call; suited to moderate-move theses where price reaches but does not vastly exceed the short strike.
How does current ANNX implied volatility affect this bull call spread?
ANNX ATM IV is at 246.10% with IV rank near 46.94%, which is mid-range against its 1-year history. Strategy selection depends more on directional thesis and expected move than on a strong IV signal.

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