Annexon, Inc. (ANNX) Volatility Skew

Implied volatility skew shows how IV varies across strike prices for a given expiration. Steeper skews indicate higher demand for downside protection relative to upside speculation.

Annexon, Inc. (ANNX) operates in the Healthcare sector, specifically the Biotechnology industry, with a market capitalization near $651.8M, listed on NASDAQ, employing roughly 106 people, carrying a beta of 1.22 to the broader market. Annexon, Inc. Led by Douglas E. Love, public since 2020-07-24.

Snapshot as of May 15, 2026.

Spot Price
$5.21
ATM IV
109.9%
IV Skew 25Δ
-2.330
IV Rank
31.1%
IV Percentile
57.5%
Term Structure Slope
-0.289

As of May 15, 2026, Annexon, Inc. (ANNX) at-the-money implied volatility is 109.9%. IV rank is 31.1% (where 0% is the 52-week low and 100% is the 52-week high). IV percentile is 57.5%. The 25-delta skew is -2.330: puts carry meaningful premium over calls, a classic equity downside-protection skew. High IV rank typically favors premium-selling strategies; low IV rank favors premium-buying.

ANNX Strategy Selection at Current Volatility Levels

For Annexon, Inc. options at 109.9% ATM IV, mid-range IV rank (31.1%) is the regime where directional conviction matters more than vol-regime positioning; strategy choice should follow the event calendar and the dealer-positioning view rather than IV rank alone. The 25-delta skew is meaningfully put-skewed, so put-credit spreads capture more premium for the same width than call-credit spreads. Pair the vol-rank read with the dealer-gamma view and the upcoming-events calendar to confirm the strategy fits both the structural regime and the path-dependent risk. The variance risk premium - the persistent gap between implied and subsequently realized vol - is positive in equity markets on average; high IV rank typically reflects a stretch where the premium is wider than usual.

Learn how volatility skew is reported and how to read the data →

Frequently asked ANNX volatility skew questions

What is the current ANNX ATM implied volatility?
As of May 15, 2026, Annexon, Inc. (ANNX) at-the-money implied volatility is 109.9%. IV rank is 31.1% on a 0-100% scale anchored to the 1-year IV range. ATM IV is the volatility input that makes a Black-Scholes-equivalent model reproduce the listed at-the-money option prices.
Is ANNX IV high or low historically?
IV is near its 1-year median, a regime where strategy choice depends on directional conviction and event calendar rather than vol regime.
What does ANNX volatility skew tell options traders?
Volatility skew is the pattern by which IV varies across strikes for a given expiration. Annexon, Inc. carries the typical equity downside-protection skew: 25-delta puts price meaningfully richer than 25-delta calls. Skew matters for risk-defined strategy selection: when downside puts are rich, put-credit spreads capture more premium; when upside calls are rich, call-credit spreads or covered-call writes harvest more.