Vertex Pharmaceuticals Incorporated (VRTX) Open Interest History

Open interest tracks the total number of outstanding options contracts. Rising OI alongside price moves can indicate growing commitment to the trend; declining OI suggests positions are being closed.

Vertex Pharmaceuticals Incorporated (VRTX) operates in the Healthcare sector, specifically the Biotechnology industry, with a market capitalization near $114.99B, listed on NASDAQ, employing roughly 6,100 people, carrying a beta of 0.30 to the broader market. Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. Led by Reshma Kewalramani, public since 1991-07-24.

Snapshot as of May 15, 2026.

Spot Price
$436.98
Call OI
26.9K
Put OI
23.8K
Total OI
50.7K
Put/Call Ratio
0.35

As of May 15, 2026, Vertex Pharmaceuticals Incorporated (VRTX) has 50.7K total contracts outstanding across all expirations. Put/call OI ratio is 0.88 (balanced positioning). Open interest reflects accumulated positions from prior sessions; persistent growth indicates sustained directional or hedging interest, while sharp drops typically mean post-expiration clean-up.

How VRTX open interest history Data Feeds Strategy Selection

Strategy selection on Vertex Pharmaceuticals Incorporated options does not derive from any single metric in isolation. The open interest history view above sits inside a broader read: ATM IV currently sits at 27.6% and dealer gamma exposure is positive, so dealer hedging is mechanically mean-reverting. Combine the open interest history data here with the volatility-skew surface, dealer-gamma exposure, max-pain level, and upcoming-events calendar to build a positioning thesis. Risk-defined structures (credit spreads, debit spreads, iron condors) are usually safer than naked positions while the regime is uncertain; the data on this page anchors the inputs but does not by itself constitute a trade thesis.

Learn how open interest is reported and how to read the data →

Frequently asked VRTX open interest history questions

What is the current VRTX options open interest?
As of May 15, 2026, Vertex Pharmaceuticals Incorporated (VRTX) has 50.7K total contracts outstanding across all listed expirations, split as 26.9K calls and 23.8K puts. Open interest reflects accumulated positions from prior trading sessions; it does not include today's volume until end-of-day reconciliation.
What is the VRTX put/call open interest ratio?
Put/call OI ratio of 0.88 is balanced.
What does VRTX open interest tell traders?
Persistent OI growth indicates sustained directional or hedging interest; sharp drops typically mean post-expiration position cleanup. Heavy OI concentrations at specific strikes act as support and resistance levels because dealer hedging amplifies near those strikes - the gamma profile of the dealer book is concentrated there. Comparing today's volume to standing OI separates opening flow from closing flow.