TLPH Straddle Strategy

TLPH (Talphera, Inc.), in the Healthcare sector, (Drug Manufacturers - Specialty & Generic industry), listed on NASDAQ.

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. Its lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, an anti-inflammatory and antiviral potential for the treatment of multiple conditions, including COVID-19, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis; Fedsyra, a pre-filled ephedrine syringe; and PFS-02, a pre-filled phenylephrine syringe. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. Talphera, Inc. was incorporated in 2005 and is headquartered in San Mateo, California.

TLPH (Talphera, Inc.) trades in the Healthcare sector, specifically Drug Manufacturers - Specialty & Generic, with a market capitalization of approximately $18.5M, a beta of 0.79 versus the broader market, a 52-week range of 0.38-1.57, average daily share volume of 188K, a public-listing history dating back to 2011, approximately 13 full-time employees. These structural characteristics shape how TLPH stock options price implied volatility around earnings windows, capital events, and macro-driven sector rotations.

A beta of 0.79 places TLPH roughly in line with broader market moves, so the strategy payoff and realized volatility track the index-equivalent baseline.

What is a straddle on TLPH?

A long straddle buys an ATM call and an ATM put at the same strike, profiting from a large move in either direction; max loss equals the combined debit when the underlying pins to the strike at expiration.

Current TLPH snapshot

As of May 15, 2026, spot at $0.84, ATM IV 124.20%, IV rank 22.79%, expected move 35.61%. The straddle on TLPH below is built from the same end-of-day chain, with strikes snapped to listed contracts and premiums pulled from the bid/ask midpoint at a 34-day expiry.

Why this straddle structure on TLPH specifically: TLPH IV at 124.20% is on the cheap side of its 1-year range, which favors premium-buying structures like a TLPH straddle, with a market-implied 1-standard-deviation move of approximately 35.61% (roughly $0.30 on the underlying). The 34-day window matched to the front-month expiry keeps theta exposure bounded while still capturing the post-snapshot move; longer-dated TLPH expiries trade a higher absolute premium for lower per-day decay. Position sizing on TLPH should anchor to the underlying notional of $0.84 per share and to the trader's directional view on TLPH stock.

TLPH straddle setup

The TLPH straddle below is built from the end-of-day chain, with each option leg priced at the bid/ask midpoint of its listed strike. With TLPH near $0.84, the first option leg uses a $0.84 strike; additional legs (when the strategy has them) anchor to spot-relative offsets. Premiums come from the bid/ask midpoint on the listed TLPH chain at a 34-day expiry; the cross-strike IV skew is reflected directly in the per-leg values rather than approximated. Quantity sizing assumes one contract per option leg (or 100 TLPH shares for the stock leg in covered calls and collars).

ActionTypeStrike / BasisPremium (est)
Buy 1Call$0.84N/A
Buy 1Put$0.84N/A

TLPH straddle risk and reward

Net Premium / Debit
N/A
Max Profit (per contract)
Unbounded
Max Loss (per contract)
Unbounded
Breakeven(s)
None on modeled curve
Risk / Reward Ratio
N/A

Upside max profit is unbounded; downside max profit is bounded at the strike minus the combined call plus put debit (reached at zero). Max loss equals the combined debit times 100 (reached when the underlying pins to the strike). Two breakevens at strike plus debit and strike minus debit.

TLPH straddle payoff curve

Modeled P&L at expiration across a range of underlying prices for the straddle on TLPH. Each row is one sampled price point from the computed payoff curve; the full curve uses 200 price points internally before being summarized into 10 rows here.

When traders use straddle on TLPH

Straddles on TLPH are pure-volatility plays that profit from large moves in either direction; traders typically buy TLPH straddles ahead of earnings, FDA decisions, or other catalysts where the realized move is expected to exceed the implied move priced into the chain.

TLPH thesis for this straddle

The market-implied 1-standard-deviation range for TLPH extends from approximately $0.54 on the downside to $1.14 on the upside. A TLPH long straddle is a pure-volatility play: it profits when the underlying moves far enough from the strike in either direction to overcome the combined call plus put debit, regardless of direction. Current TLPH IV rank near 22.79% sits in the lower third of its 1-year distribution, where IV often re-expands toward the mean; this favors premium-buying structures and disadvantages premium-selling structures on TLPH at 124.20%. As a Healthcare name, TLPH options can move on sector-level news flow (peer earnings, regulatory updates, industry-specific macro data) in addition to TLPH-specific events.

TLPH straddle positions are structurally neutral / high-volatility (long premium); the modeled P&L assumes European-style exercise at expiration and ignores early assignment, transaction costs, dividends paid before expiry on the stock leg (when present), and the bid-ask spread on the listed chain. TLPH positions also carry Healthcare sector concentration risk; news flow inside the sector (peer earnings, regulatory shifts, supply-chain headlines) can move TLPH alongside the broader basket even when TLPH-specific fundamentals are unchanged. Always rebuild the position from current TLPH chain quotes before placing a trade.

Frequently asked questions

What is a straddle on TLPH?
A straddle on TLPH is the straddle strategy applied to TLPH (stock). The strategy is structurally neutral / high-volatility (long premium): A long straddle buys an ATM call and an ATM put at the same strike, profiting from a large move in either direction; max loss equals the combined debit when the underlying pins to the strike at expiration. With TLPH stock trading near $0.84, the strikes shown on this page are snapped to the nearest listed TLPH chain strike and the premiums come straight from the end-of-day bid/ask midpoint.
How are TLPH straddle max profit and max loss calculated?
Upside max profit is unbounded; downside max profit is bounded at the strike minus the combined call plus put debit (reached at zero). Max loss equals the combined debit times 100 (reached when the underlying pins to the strike). Two breakevens at strike plus debit and strike minus debit. For the TLPH straddle priced from the end-of-day chain at a 30-day expiry (ATM IV 124.20%), the computed maximum profit is unbounded per contract and the computed maximum loss is unbounded per contract. Live intraday quotes will differ as the chain moves through the trading session.
What is the breakeven for a TLPH straddle?
The breakeven for the TLPH straddle priced on this page is no defined breakeven on the modeled curve at expiration, derived from end-of-day chain premiums. Breakeven is the underlying price at which the strategy's P&L crosses zero ignoring transaction costs and assignment risk. The current TLPH market-implied 1-standard-deviation expected move is approximately 35.61%; if the move sits well outside the breakeven distance, the structure's risk-reward becomes correspondingly tighter.
When should you consider a straddle on TLPH?
Straddles on TLPH are pure-volatility plays that profit from large moves in either direction; traders typically buy TLPH straddles ahead of earnings, FDA decisions, or other catalysts where the realized move is expected to exceed the implied move priced into the chain.
How does current TLPH implied volatility affect this straddle?
TLPH ATM IV is at 124.20% with IV rank near 22.79%, which is on the low end of its 1-year range. Premium-buying structures (long call, long put, debit spreads) are relatively cheap in this regime; premium-selling structures collect less credit per unit risk.

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