Krystal Biotech, Inc. (KRYS) Volatility Skew

Implied volatility skew shows how IV varies across strike prices for a given expiration. Steeper skews indicate higher demand for downside protection relative to upside speculation.

Krystal Biotech, Inc. (KRYS) operates in the Healthcare sector, specifically the Biotechnology industry, with a market capitalization near $9.21B, listed on NASDAQ, employing roughly 275 people, carrying a beta of 0.49 to the broader market. Krystal Biotech, Inc. Led by Krish S. Krishnan, public since 2017-09-20.

Snapshot as of May 14, 2026.

Spot Price
$315.13
ATM IV
37.7%
IV Skew 25Δ
0.042
IV Rank
10.0%
IV Percentile
5.6%
Term Structure Slope
0.006

As of May 14, 2026, Krystal Biotech, Inc. (KRYS) at-the-money implied volatility is 37.7%. IV rank is 10.0% (where 0% is the 52-week low and 100% is the 52-week high). IV percentile is 5.6%. The 25-delta skew is +0.042: calls carry premium over puts, indicating upside speculation or squeeze risk. High IV rank typically favors premium-selling strategies; low IV rank favors premium-buying.

KRYS Strategy Selection at Current Volatility Levels

For Krystal Biotech, Inc. options at 37.7% ATM IV, low IV rank (10.0%) favors premium-buying or long-vol structures: long calls or puts, debit spreads, calendar spreads, long straddles. The risk: low-rank regimes can persist for months while time decay eats premium-buyers alive. The 25-delta skew tilts to calls, so call-credit spreads or covered-call writes harvest more premium than put-credit spreads of the same width. Pair the vol-rank read with the dealer-gamma view and the upcoming-events calendar to confirm the strategy fits both the structural regime and the path-dependent risk. The variance risk premium - the persistent gap between implied and subsequently realized vol - is positive in equity markets on average; high IV rank typically reflects a stretch where the premium is wider than usual.

Learn how volatility skew is reported and how to read the data →

KRYS highest implied-volatility contracts

TypeStrikeExpirationVolumeOIIVBidAsk
CALL$310.00Jun 18, 2026178737.6%$12.50$15.70
CALL$320.00Aug 21, 2026076243.8%$22.80$26.50

Top 2 contracts from the ORATS-sourced nightly scan; ranked by iv within the broader S&P 500/400/600 + ETF universe.

Frequently asked KRYS volatility skew questions

What is the current KRYS ATM implied volatility?
As of May 14, 2026, Krystal Biotech, Inc. (KRYS) at-the-money implied volatility is 37.7%. IV rank is 10.0% on a 0-100% scale anchored to the 1-year IV range. ATM IV is the volatility input that makes a Black-Scholes-equivalent model reproduce the listed at-the-money option prices.
Is KRYS IV high or low historically?
IV is subdued relative to its 1-year history, conditions that typically favor premium-buying strategies (long calls, long puts, debit spreads, calendar spreads).
What does KRYS volatility skew tell options traders?
Volatility skew is the pattern by which IV varies across strikes for a given expiration. Krystal Biotech, Inc. shows upside-skewed pricing: 25-delta calls trade richer than 25-delta puts, often reflecting upside speculation or squeeze risk. Skew matters for risk-defined strategy selection: when downside puts are rich, put-credit spreads capture more premium; when upside calls are rich, call-credit spreads or covered-call writes harvest more.