ARWR Strangle Strategy

ARWR (Arrowhead Pharmaceuticals, Inc.), in the Healthcare sector, (Biotechnology industry), listed on NASDAQ.

Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways.

ARWR (Arrowhead Pharmaceuticals, Inc.) trades in the Healthcare sector, specifically Biotechnology, with a market capitalization of approximately $12.20B, a beta of 1.29 versus the broader market, a 52-week range of 19.42-95.49, average daily share volume of 2.0M, a public-listing history dating back to 1993, approximately 711 full-time employees. These structural characteristics shape how ARWR stock options price implied volatility around earnings windows, capital events, and macro-driven sector rotations.

A beta of 1.29 places ARWR roughly in line with broader market moves, so the strategy payoff and realized volatility track the index-equivalent baseline.

What is a strangle on ARWR?

A long strangle buys an OTM call and an OTM put at offset strikes, cheaper than a straddle but requiring a larger underlying move to profit since both wings start out-of-the-money.

ARWR snapshot

As of August 14, 2026, spot at $86.83, ATM IV 49.00%, IV rank 7.80%, expected move 14.05%. The strangle on ARWR below is built from the August 14, 2026 end-of-day chain, with strikes snapped to listed contracts and premiums pulled from the bid/ask midpoint at a 35-day expiry.

Why this strangle structure on ARWR specifically: ARWR IV at 49.00% is on the cheap side of its 1-year range, which favors premium-buying structures like a ARWR strangle, with a market-implied 1-standard-deviation move of approximately 14.05% (roughly $12.20 on the underlying). The 35-day window matched to the front-month expiry keeps theta exposure bounded while still capturing the post-snapshot move; longer-dated ARWR expiries trade a higher absolute premium for lower per-day decay. Position sizing on ARWR should anchor to the underlying notional of $86.83 per share and to the trader's directional view on ARWR stock.

ARWR strangle setup

The ARWR strangle below is built from the August 14, 2026 end-of-day chain, with each option leg priced at the bid/ask midpoint of its listed strike. With ARWR at $86.83 on that close, the first option leg uses a $90.00 strike; additional legs (when the strategy has them) anchor to spot-relative offsets. Premiums come from the bid/ask midpoint on the listed ARWR chain at a 35-day expiry; the cross-strike IV skew is reflected directly in the per-leg values rather than approximated. Quantity sizing assumes one contract per option leg (or 100 ARWR shares for the stock leg in covered calls and collars).

ActionTypeStrike / BasisPremium (est)
Buy 1Call$90.00$3.95
Buy 1Put$82.50$3.35

ARWR strangle risk and reward

Net Premium / Debit
-$730.00
Max Profit (per contract)
Unbounded
Max Loss (per contract)
-$730.00
Breakeven(s)
$75.20, $97.30
Risk / Reward Ratio
Unbounded

Upside max profit is unbounded; downside max profit is bounded at the put strike minus the combined debit (reached at zero). Max loss equals the combined debit times 100 (reached anywhere between the two OTM strikes). Two breakevens at call-strike plus debit and put-strike minus debit.

ARWR strangle payoff curve

Modeled P&L at expiration across a range of underlying prices for the strangle on ARWR. Each row is one sampled price point from the computed payoff curve; the full curve uses 200 price points internally before being summarized into 10 rows here.

ARWR strangle profit and loss curve at expiration with breakevens and current spot markedARWR strangle payoff at expiration$0$2000$4000$6000$20$40$60$80$100$120$140$160Underlying Price ($)P&L at Expiration ($)BE $75.20BE $97.30Spot $86.83
P&L at expiration across the modeled underlying-price range. Green shading marks profitable regions, red shading marks loss regions. Dotted purple verticals mark breakevens; the solid dark vertical marks current spot.
Underlying Price% From SpotP&L at Expiration
$0.01-100.0%+$7,519.00
$19.21-77.9%+$5,599.25
$38.40-55.8%+$3,679.50
$57.60-33.7%+$1,759.75
$76.80-11.6%-$159.99
$96.00+10.6%-$130.26
$115.19+32.7%+$1,789.49
$134.39+54.8%+$3,709.24
$153.59+76.9%+$5,628.99
$172.79+99.0%+$7,548.74

When traders use strangle on ARWR

Strangles on ARWR are the cheaper cousin of the straddle - traders use them when they want a large directional move but are willing to give up the inner-strike sensitivity in exchange for a lower up-front debit on the ARWR chain.

ARWR thesis for this strangle

The market-implied 1-standard-deviation range for ARWR extends from approximately $74.63 on the downside to $99.03 on the upside. A ARWR long strangle is the OTM cousin of the straddle: lower up-front cost but the underlying has to travel further past either OTM strike before the position turns profitable at expiration. Current ARWR IV rank near 7.80% sits in the lower third of its 1-year distribution, where IV often re-expands toward the mean; this favors premium-buying structures and disadvantages premium-selling structures on ARWR at 49.00%. As a Healthcare name, ARWR options can move on sector-level news flow (peer earnings, regulatory updates, industry-specific macro data) in addition to ARWR-specific events.

ARWR strangle positions are structurally neutral / high-volatility (long premium, OTM); the modeled P&L assumes European-style exercise at expiration and ignores early assignment, transaction costs, dividends paid before expiry on the stock leg (when present), and the bid-ask spread on the listed chain. ARWR positions also carry Healthcare sector concentration risk; news flow inside the sector (peer earnings, regulatory shifts, supply-chain headlines) can move ARWR alongside the broader basket even when ARWR-specific fundamentals are unchanged. Always rebuild the position from current ARWR chain quotes before placing a trade.

Frequently asked questions

What is a strangle on ARWR?
A strangle on ARWR is the strangle strategy applied to ARWR (stock). The strategy is structurally neutral / high-volatility (long premium, OTM): A long strangle buys an OTM call and an OTM put at offset strikes, cheaper than a straddle but requiring a larger underlying move to profit since both wings start out-of-the-money. With ARWR stock at $86.83 on the August 14, 2026 close, the strikes shown on this page are snapped to the nearest listed ARWR chain strike and the premiums come straight from that session's bid/ask midpoint.
How are ARWR strangle max profit and max loss calculated?
Upside max profit is unbounded; downside max profit is bounded at the put strike minus the combined debit (reached at zero). Max loss equals the combined debit times 100 (reached anywhere between the two OTM strikes). Two breakevens at call-strike plus debit and put-strike minus debit. For the ARWR strangle priced from the August 14, 2026 end-of-day chain at a 30-day expiry (ATM IV 49.00%), the computed maximum profit is unbounded per contract and the computed maximum loss is -$730.00 per contract. Live intraday quotes will differ as the chain moves through the trading session.
What is the breakeven for a ARWR strangle?
The breakeven for the ARWR strangle priced on this page is roughly $75.20 and $97.30 at expiration, derived from the August 14, 2026 end-of-day chain's premiums. Breakeven is the underlying price at which the strategy's P&L crosses zero ignoring transaction costs and assignment risk. The ARWR market-implied 1-standard-deviation expected move in the same options snapshot is approximately 14.05%; if the move sits well outside the breakeven distance, the structure's risk-reward becomes correspondingly tighter.
When should you consider a strangle on ARWR?
Strangles on ARWR are the cheaper cousin of the straddle - traders use them when they want a large directional move but are willing to give up the inner-strike sensitivity in exchange for a lower up-front debit on the ARWR chain.
How does current ARWR implied volatility affect this strangle?
ARWR ATM IV is at 49.00% with IV rank near 7.80%, which is on the low end of its 1-year range. Premium-buying structures (long call, long put, debit spreads) are relatively cheap in this regime; premium-selling structures collect less credit per unit risk.

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