ANAB Insider Trading

AnaptysBio, Inc. (ANAB) operates in the Healthcare sector, specifically the Biotechnology industry, with a market capitalization near $1.40B, listed on NASDAQ, employing roughly 104 people, carrying a beta of 0.41 to the broader market. AnaptysBio, Inc. Led by Daniel Faga, public since 2017-01-26.

In the last 12 months, AnaptysBio, Inc. insiders made 0 buy transactions and 42 sale transactions.

DateNameTypeSharesPriceValue
Oct 2, 2026RENTON HOLLINGSM-Exempt5,000$18.03$90.2K
Oct 2, 2026RENTON HOLLINGSS-Sale5,000$49.87$249.4K
Oct 2, 2026RENTON HOLLINGSM-Exempt5,000$18.03$90.2K
Sep 17, 2026Orwin John AM-Exempt1,300$0.00$0
Sep 17, 2026Orwin John AM-Exempt1,300$0.00$0
Aug 7, 2026Lizzul Paul F.A-Award16,667$0.00$0
Aug 7, 2026Faga DanielA-Award53,334$0.00$0
Jun 17, 2026Schmid John P.M-Exempt6,030$0.00$0
Jun 17, 2026Schmid John P.M-Exempt6,030$0.00$0
Jun 17, 2026RENTON HOLLINGSM-Exempt6,030$0.00$0

ANAB Insider Activity by Quarter

Reported Form 4 and Form 5 lines under ANAB's own SEC company ID, by transaction date, back to Q4 2024. Purchases and sales are code P / S (open market or private) in the company's shares; other lines are purchases and sales of other securities (options, warrants, preferred), awards, exercises, tax withholding, gifts and other acquisitions and dispositions. Later filings and amendments can change the current quarter. Earlier quarters are not shown: the filings read reach back to Feb 25, 2021, and a quarter counts only when every filing for it was read.

QuarterPurchasesBoughtSalesSoldOther Lines
Q4 2026 (so far)0N/A1$249.4K2
Q3 20260N/A0N/A2
Q2 20260N/A0N/A74
Q1 20260N/A31$6.5M53
Q4 20250N/A10$3.0M15
Q3 20250N/A5$932.9K8
Q2 20250N/A2$144.5K15
Q1 20251$86.1K0N/A51
Q4 20242$1.0M1$250.0K2

ANAB Institutional Ownership (13F)

As of Jun 30, 2026 (Q2 2026), 213 institutions reported holding 30,132,196 ANAB shares, valued at $2.05B as reported, 113.2% of its market cap (market cap of Jun 26, 2026). That is +5 institutions from the quarter before. Among managers whose reports for both quarters are comparable, 43 opened a position, 34 closed one, 23 added and 144 trimmed.

Top Holders, Q2 2026

ManagerSharesValueChange
EcoR1 Capital, LLC7,880,094$531.9M-3,940,047
BlackRock, Inc.1,844,049$124.5M-678,021
TANG CAPITAL MANAGEMENT LLC1,330,879$89.8M-665,440
STATE STREET CORP1,286,194$86.8M-202,474
VANGUARD CAPITAL MANAGEMENT LLC906,233$61.2M-373,494
Affinity Asset Advisors, LLC826,109$55.8M-583,891
Sanofi821,917$55.5M-410,959
MILLENNIUM MANAGEMENT LLC807,316$54.5M+93,958
Woodline Partners LP717,014$48.4M+200,630
683 Capital Management, LLC660,000$44.6M-277,500

By Quarter

QuarterInstitutionsSharesValue
Q2 202621330,132,196$2.05B
Q1 202620828,251,892$1.55B
Q4 202517929,354,491$1.42B
Q3 202516631,685,633$980.6M
Q2 202514736,776,587$816.4M
Q1 202515340,052,771$744.6M
Q4 202413535,417,710$468.9M
Q3 202416033,662,678$1.13B
Q2 202413529,900,162$749.3M

From the SEC's Form 13F data sets: investment managers with $100 million or more in Section 13(f) securities report their holdings each quarter, up to 45 days after it ends; a restated filing replaces the original, and values are as the managers reported them (a position whose price runs about 1,000 times below other managers', from a manager whose positions mostly do, is read as reported in thousands of dollars). The same shares can be reported by more than one manager, so totals can count some twice.

ETFs Holding ANAB

FundWeight of ANABShares (as reported)Value (as reported)Source updated
VTI Vanguard Morningstar Total Stock Market ETF0.00%648,146$37.0MOct 7, 2026
XBI State Street SPDR S&P Biotech ETF0.30%648,973$30.0MOct 8, 2026
IWM iShares Russell 2000 ETF0.03%529,635$24.2MOct 8, 2026
VXF Vanguard Extended Market ETF0.01%239,419$13.7MOct 7, 2026
IBB iShares Biotechnology ETF0.09%209,169$9.5MOct 8, 2026
PBE Invesco Biotechnology & Genome ETF2.22%200,573$9.2MOct 8, 2026
IWO iShares Russell 2000 Growth ETF0.06%187,224$8.5MOct 8, 2026
VTWO Vanguard Russell 2000 ETF0.04%113,596$6.5MOct 7, 2026
FYC First Trust Small Cap Growth AlphaDEX Fund0.47%136,138$6.2MOct 8, 2026
SCHA Schwab U.S. Small-Cap ETF0.02%113,114$5.3MOct 8, 2026
PSC Principal U.S. Small-Cap Multi-Factor ETF0.17%99,222$4.5MOct 8, 2026
SFLO VictoryShares Small Cap Free Cash Flow ETF0.43%75,598$3.5MOct 8, 2026
VHT Vanguard Health Care ETF0.01%54,227$3.1MOct 7, 2026
FYX First Trust Small Cap Core AlphaDEX Fund0.17%50,006$2.3MOct 8, 2026
FSMD Fidelity Small-Mid Multifactor ETF0.08%44,990$2.1MOct 8, 2026

From each fund's latest holdings file on record that shows ANAB's listed security itself. A file counts when its line count is consistent with the fund's reported holdings count (at most twice it plus 10, or at most 1,000 lines for a reported count of exactly 10, which the data source gives many funds as a cap), read with that file or inherited from the fund's last classified file (within 20% of its line count, read within 60 days). Funds whose line for the company could not be confirmed as ANAB's listed security, or that hold it through underlying funds (look-through), are not listed. Only long positions count: a fund is left out when any of its lines for ANAB reports a negative weight, share count or value, or none of them above zero (a short position, or figures that disagree). Shares, value and weight are as reported in each fund's file, dated by the data source's last update of that file (not the date of the positions); the weight is ANAB's share of that fund.

How to Read ANAB Insider Activity

Net insider sentiment skews to the sell side over the trailing twelve months: 42 sales versus 0 buys. Insider sales carry less informational weight than buys because they are often driven by liquidity, tax planning, or pre-scheduled Rule 10b5-1 trading plans rather than negative information. The transaction type alone does not say whether a sale was made on the open market or privately, or under a 10b5-1 plan; the filing's plan checkbox and footnotes do. The transaction table above includes the filer's reporting name, transaction type, share count, per-share price, and total dollar value where computable. For options traders, insider activity is one input to event-driven sizing alongside earnings calendar, analyst-rating cluster moves, and the implied-vol surface. Form 4 filings (the dominant Section 16 reporting form) must be submitted within two business days of the transaction; clusters of buys across multiple insiders within a short window are the strongest informational pattern. SEC EDGAR carries the underlying source filings for verification and additional historical depth.

Learn how insider trading is reported and how to read the data →

Frequently asked ANAB insider trading questions

How active are ANAB insiders right now?
Over the trailing twelve months, AnaptysBio, Inc. (ANAB) insiders made 0 buy transactions and 42 sale transactions. Net insider sentiment over the trailing twelve months tilts to the sell side (42 sales vs 0 buys). The transaction list above shows the most recent filings; each entry includes the insider's name, transaction type, share count, and per-share price.
What counts as an insider transaction?
Section 16 of the Securities Exchange Act requires officers, directors, and 10% beneficial-owner shareholders to disclose changes in their holdings via Form 3 (initial statement), Form 4 (subsequent transactions, filed within two business days), and Form 5 (annual catch-up). Insider transactions cover open-market purchases and sales, exercise of stock options, gifts, and grants. The "transaction type" field on each row distinguishes these subcategories.
Are ANAB insider buys a bullish signal?
Insider purchases (Type P, made on the open market or privately; the code covers both) carry more informational weight than insider sales: an insider must commit personal capital, and the SEC scrutinizes purchases under Rule 10b5-1 for material non-public information. Sales, by contrast, are often driven by liquidity, tax planning, or pre-scheduled 10b5-1 trading plans rather than negative information. Cluster buying (multiple insiders buying within a short window) is a stronger signal than isolated buys.
How do ANAB insider transactions affect options pricing?
Insider transaction data does not directly drive implied volatility, but Form 4 disclosures can move single-name IV if the size or timing is unusual (e.g. a large CEO buy ahead of an earnings window). Options markets price the marginal informational content; routine transactions under pre-scheduled plans are typically ignored. For event-driven options sizing, pair the insider transaction history with the upcoming earnings calendar.