ALNY Insider Trading

Alnylam Pharmaceuticals, Inc. (ALNY) operates in the Healthcare sector, specifically the Biotechnology industry, with a market capitalization near $29.95B, listed on NASDAQ, employing roughly 2,500 people, carrying a beta of 0.27 to the broader market. Alnylam Pharmaceuticals, Inc. Led by Yvonne L. Greenstreet, public since 2004-06-01.

In the last 12 months, Alnylam Pharmaceuticals, Inc. insiders made 0 buy transactions and 279 sale transactions.

DateNameTypeSharesPriceValue
Oct 6, 2026SUPRAN BRYANS-Sale1,758$226.88$398.9K
Sep 22, 2026Greenstreet YvonneA-Award107$0.00$0
Jun 3, 2026PYOTT DAVID E IM-Exempt3,830$0.00$0
Jun 3, 2026PYOTT DAVID E IS-Sale921$297.71$274.2K
Jun 3, 2026PYOTT DAVID E IS-Sale1,175$298.91$351.2K
Jun 3, 2026PYOTT DAVID E IS-Sale1,222$299.87$366.4K
Jun 3, 2026PYOTT DAVID E IS-Sale495$300.72$148.9K
Jun 3, 2026PYOTT DAVID E IS-Sale17$302.65$5.1K
Jun 3, 2026PYOTT DAVID E IM-Exempt3,830$70.20$268.9K
Jun 3, 2026Cravatt BenjaminA-Award4,393$295.63$1.3M

ALNY Insider Activity by Quarter

Reported Form 4 and Form 5 lines under ALNY's own SEC company ID, by transaction date, back to Q4 2024. Purchases and sales are code P / S (open market or private) in the company's shares; other lines are purchases and sales of other securities (options, warrants, preferred), awards, exercises, tax withholding, gifts and other acquisitions and dispositions. Later filings and amendments can change the current quarter. Earlier quarters are not shown: the filings read reach back to Mar 1, 2024, and a quarter counts only when every filing for it was read.

QuarterPurchasesBoughtSalesSoldOther Lines
Q4 2026 (so far)0N/A1$398.9K0
Q3 20260N/A0N/A1
Q2 20260N/A19$2.4M23
Q1 20260N/A228$24.0M33
Q4 20250N/A96$27.3M27
Q3 20250N/A80$35.5M22
Q2 20250N/A17$16.8M32
Q1 20250N/A152$29.1M36
Q4 20241$1.2K36$3.7M7

ALNY Institutional Ownership (13F)

As of Jun 30, 2026 (Q2 2026), 788 institutions reported holding 133,498,237 ALNY shares, valued at $40.16B as reported, 103.7% of its market cap (market cap of Jun 26, 2026). That is -5 institutions from the quarter before. Among managers whose reports for both quarters are comparable, 75 opened a position, 68 closed one, 324 added and 279 trimmed.

Top Holders, Q2 2026

ManagerSharesValueChange
FMR LLC15,023,962$4.52B+444,796
Capital World Investors11,144,846$3.35B+342,498
BlackRock, Inc.10,907,675$3.28B+462,767
Capital Research Global Investors9,750,699$2.94B+279,518
VANGUARD PORTFOLIO MANAGEMENT LLC6,538,390$1.97B+47,110
VANGUARD CAPITAL MANAGEMENT LLC6,029,478$1.82B+82,772
T. Rowe Price Investment Management, Inc.5,642,173$1.70B+448,849
Invesco Ltd.3,754,318$1.13B-320,802
STATE STREET CORP3,555,689$1.07B+232,991
JPMORGAN CHASE & CO2,675,517$785.3M-3,648,235

By Quarter

QuarterInstitutionsSharesValue
Q2 2026788133,498,237$40.16B
Q1 2026793131,400,360$43.37B
Q4 2025852134,075,013$53.23B
Q3 2025820134,374,512$61.25B
Q2 2025650132,497,934$43.20B
Q1 2025615127,249,569$34.24B
Q4 2024584127,735,449$30.05B
Q3 2024558123,546,851$33.97B
Q2 2024516122,614,109$29.80B

From the SEC's Form 13F data sets: investment managers with $100 million or more in Section 13(f) securities report their holdings each quarter, up to 45 days after it ends; a restated filing replaces the original, and values are as the managers reported them (a position whose price runs about 1,000 times below other managers', from a manager whose positions mostly do, is read as reported in thousands of dollars). The same shares can be reported by more than one manager, so totals can count some twice.

ETFs Holding ALNY

FundWeight of ALNYShares (as reported)Value (as reported)Source updated
VTI Vanguard Morningstar Total Stock Market ETF0.04%4,243,911$1.02BOct 7, 2026
VO Vanguard Morningstar Mid-Cap ETF0.31%2,887,944$695.1MOct 7, 2026
QQQ Invesco QQQ Trust, Series 10.12%2,770,062$621.6MOct 8, 2026
VUG Vanguard Morningstar Growth ETF0.10%1,609,611$387.4MOct 7, 2026
VXF Vanguard Extended Market ETF0.38%1,551,082$373.3MOct 7, 2026
VOT Vanguard Morningstar Mid-Cap Growth ETF0.72%1,025,675$246.9MOct 7, 2026
IBB iShares Biotechnology ETF2.17%1,009,066$226.4MOct 8, 2026
TCAF T. Rowe Capital Appreciation Equity ETF1.99%807,515$180.8MOct 8, 2026
CGGR Capital Group Growth ETF0.66%781,376$175.0MOct 8, 2026
IWP iShares Russell Mid-Cap Growth ETF0.85%751,209$168.6MOct 8, 2026
QQQM Invesco NASDAQ 100 ETF0.12%619,827$139.1MOct 8, 2026
XBI State Street SPDR S&P Biotech ETF1.31%580,429$132.1MOct 8, 2026
IWR iShares Russell Mid-Cap ETF0.22%550,985$123.6MOct 8, 2026
USMV iShares MSCI USA Min Vol Factor ETF0.52%541,740$121.6MOct 8, 2026
IWF iShares Russell 1000 Growth ETF0.09%500,632$112.3MOct 8, 2026

From each fund's latest holdings file on record that shows ALNY's listed security itself. A file counts when its line count is consistent with the fund's reported holdings count (at most twice it plus 10, or at most 1,000 lines for a reported count of exactly 10, which the data source gives many funds as a cap), read with that file or inherited from the fund's last classified file (within 20% of its line count, read within 60 days). Funds whose line for the company could not be confirmed as ALNY's listed security, or that hold it through underlying funds (look-through), are not listed. Only long positions count: a fund is left out when any of its lines for ALNY reports a negative weight, share count or value, or none of them above zero (a short position, or figures that disagree). Shares, value and weight are as reported in each fund's file, dated by the data source's last update of that file (not the date of the positions); the weight is ALNY's share of that fund.

ALNY Congress Trades

Members of Congress and their households disclosed 6 transactions in ALNY on file (2 purchases, 4 sales) by 4 members, the latest trade on Aug 11, 2026.

MemberChamberTypeAmountTradedDisclosed
Cory A. Booker (D-NJ)SenateSale (Full)$1,001 - $15,000Aug 11, 2026Sep 9, 2026
Jefferson Shreve (R-IN-6)HouseSale (Full)$15,001 - $50,000May 12, 2025Jun 23, 2025
Josh Gottheimer (D-NJ-5)HouseSale (Full)$1,001 - $15,000Jan 29, 2024Feb 15, 2024
Josh Gottheimer (D-NJ-5)HousePurchase$1,001 - $15,000Jan 11, 2024Feb 15, 2024
Josh Gottheimer (D-NJ-5)HouseSale (Full)$1,001 - $15,000Dec 11, 2023Jan 7, 2024
Daniel S. Goldman (D-NY-10)HousePurchase$15,001 - $50,000Mar 6, 2023Apr 17, 2023

From the periodic transaction reports members of the Senate and the House file under the STOCK Act, within 45 days of a trade (some file later); amounts are the ranges the reports give (a few give an exact amount), and a transaction a later report lists again is counted once. On file: House reports disclosed from Apr 10, 2023 through Oct 13, 2026; Senate reports disclosed from Jan 30, 2014 through Oct 7, 2026. The party is the member's on the trade date. A trade is listed under the company that traded under its ticker on the trade date (dated from Feb 1, 2021, unless the filing describes another company of ours; before that, only when the filing's description of the security is the company's name).

How to Read ALNY Insider Activity

Net insider sentiment skews to the sell side over the trailing twelve months: 279 sales versus 0 buys. Insider sales carry less informational weight than buys because they are often driven by liquidity, tax planning, or pre-scheduled Rule 10b5-1 trading plans rather than negative information. The transaction type alone does not say whether a sale was made on the open market or privately, or under a 10b5-1 plan; the filing's plan checkbox and footnotes do. The transaction table above includes the filer's reporting name, transaction type, share count, per-share price, and total dollar value where computable. For options traders, insider activity is one input to event-driven sizing alongside earnings calendar, analyst-rating cluster moves, and the implied-vol surface. Form 4 filings (the dominant Section 16 reporting form) must be submitted within two business days of the transaction; clusters of buys across multiple insiders within a short window are the strongest informational pattern. SEC EDGAR carries the underlying source filings for verification and additional historical depth.

Learn how insider trading is reported and how to read the data →

Frequently asked ALNY insider trading questions

How active are ALNY insiders right now?
Over the trailing twelve months, Alnylam Pharmaceuticals, Inc. (ALNY) insiders made 0 buy transactions and 279 sale transactions. Net insider sentiment over the trailing twelve months tilts to the sell side (279 sales vs 0 buys). The transaction list above shows the most recent filings; each entry includes the insider's name, transaction type, share count, and per-share price.
What counts as an insider transaction?
Section 16 of the Securities Exchange Act requires officers, directors, and 10% beneficial-owner shareholders to disclose changes in their holdings via Form 3 (initial statement), Form 4 (subsequent transactions, filed within two business days), and Form 5 (annual catch-up). Insider transactions cover open-market purchases and sales, exercise of stock options, gifts, and grants. The "transaction type" field on each row distinguishes these subcategories.
Are ALNY insider buys a bullish signal?
Insider purchases (Type P, made on the open market or privately; the code covers both) carry more informational weight than insider sales: an insider must commit personal capital, and the SEC scrutinizes purchases under Rule 10b5-1 for material non-public information. Sales, by contrast, are often driven by liquidity, tax planning, or pre-scheduled 10b5-1 trading plans rather than negative information. Cluster buying (multiple insiders buying within a short window) is a stronger signal than isolated buys.
How do ALNY insider transactions affect options pricing?
Insider transaction data does not directly drive implied volatility, but Form 4 disclosures can move single-name IV if the size or timing is unusual (e.g. a large CEO buy ahead of an earnings window). Options markets price the marginal informational content; routine transactions under pre-scheduled plans are typically ignored. For event-driven options sizing, pair the insider transaction history with the upcoming earnings calendar.